Verrucous carcinoma in recessive dystrophic epidermolysis bullosa.

How to Cite

Inverardi T. 2011. Verrucous carcinoma in recessive dystrophic epidermolysis bullosa. Eur. J. Pediat. Dermatol. 21 (4): 251.

Authors

Inverardi T.
pp. 251

Abstract

Case report. A 34-year-old male was followed from the first year of life because of recessive dystrophic epidermolysis bullosa (RDEB) Hallopeau-Siemens type, with severe skin lesions responsible for mitten deformity of the hand, eye damage, gastrointestinal problems and chronic anemia; the renal function was preserved. When aged 32 years he had been operated for a hyperkeratotic and ulcerated nodule of the dorsal aspect of the right hand which on histological examination resulted keratoacanthoma. Soon after he presented a slow growing hyperkeratotic lesion of the medial surface of the right foot (Fig. 1). Under regional anesthesia the neoformation was removed by curettage till to the mid-dermis (Fig. 2), leaving the surgical wound to heal for second intention (Fig. 3). The histological diagnosis (Fig. 4 and inset) was verrucous carcinoma. The patient is now under continuous clinical monitoring.

Keywords

Verrucous carcinoma, Recessive dystrophic epidermolysis bullosa