Drug rash with eosinophilia and systemic symptoms (DRESS) due to lamotrigine in a 12-year-old girl.

How to Cite

Neri I., Virdi A., Piccolo V., Patrizi A. 2011. Drug rash with eosinophilia and systemic symptoms (DRESS) due to lamotrigine in a 12-year-old girl. Eur. J. Pediat. Dermatol. 21 (1):7-10.

Authors

Neri I. Virdi A. Piccolo V. Patrizi A.
pp. 7-10

Abstract

Drug rash with eosinophilia and systemic symptoms (DRESS) is a rare, but potentially
severe drug reaction, occurring about 3-6 weeks after drug administration and characterized
by morbilliform skin rash, fever, lymphadenopathy, eosinophilia and single or multiple
organ involvement. We report a case of a 12-year-old girl, treated with lamotrigine for epilepsy
and developing DRESS due to this drug. Clinical and laboratory findings along with
some pathogenetic hypotheses are also discussed.

Keywords

DRESS, Drug reaction, Hypersensitivity reaction, Lamotrigine, Eosinophilia