Relationship between collagen disorders and hidradenitis suppurativa regarding two cases of Loeys-Dietz syndrome.

DOI:

https://doi.org/10.26326/2281-9649.33.2.2446

How to Cite

Vultaggio M., Diluvio L., Artosi F., Cannizzaro M.V., Bertoldo F., Ruvolo G., Campione E., Bianchi L. 2023. Relationship between collagen disorders and hidradenitis suppurativa regarding two cases of Loeys-Dietz syndrome. Eur. J. Pediat. Dermatol. 33 (2):116-9. 10.26326/2281-9649.33.2.2446.

Authors

Vultaggio M. Diluvio L. Artosi F. Cannizzaro M.V. Bertoldo F. Ruvolo G. Campione E. Bianchi L.
pp. 116-9

Abstract

Loeys-Dietz syndrome (LDs) is an inherited disorder characterized by connective tissue changes similar to those that occur in Ehlers-Danlos and Marfan syndrome. The authors describe two new cases of this syndrome, noting among the cutaneous signs the presence of hidradenitis suppurativa (HS) localized also in atypical sites. Since a higher incidence of HS has been reported in other diseases characterized by collagen disorders, such as Ehler-Danlos syndrome, Marfan syndrome, autoimmune spondyloarthropathies, lichen sclerosus, dyselastic striae, the authors discuss the significance of such alterations in the pathogenesis of HS.

Keywords

connective tissue disorders, acne inversa, genetic disease, Loeys-Dietz syndrome